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Writing Assignment – Improving Aviation Safety
Writing Assignment – Improving Aviation Safety
For this assignment, conduct research and argue the importance of SMS and the NTSB in accident prevention. Access NTSB’s Aviation Accident Database & SynopsesLinks to an external site. to identify an aircraft accident investigation that has been completed. You may choose any type of aircraft and accident that you wish. Then, write a 2-3 page paper, not including the title page and reference page, that explains the accident, the findings, and considers the role of the NTSB, coupled with effective SMS principles, in preventing a similar accident from occurring.
Your paper must be supported by a minimum of three scholarly references, should be grammatically sound, and free of spelling errors. You must include a properly formatted title page, in-text citations where appropriate, and a reference page formatted according to current APA guidelines. If you have any questions regarding APA requirements, please refer to the current APA manual or ask your instructor.
Please refer to the rubric to ensure that you have a thorough understanding of the expectations and grading scale for this activity.
Save your assignment using a naming convention that includes your first and last name and the activity number (or description). Do not add punctuation or special characters.
Your paper will automatically be evaluated through Turnitin when you submit your assignment in this activity. Turnitin is a service that checks your work for improper citation or potential plagiarism by comparing it against a database of web pages, student papers, and articles from academic books and publications.
Gene coexpression network analysis for time series single cell data
Gene coexpression network analysis for time series single cell data
Objectives:
1. Coexpression analysis (correlation) and network construction of time series single cell data
2. Creating a package (pipeline) for the entire analysis process
3. Evaluating the pipeline with the existing packages in this paper (see: https://doi.org/10.1016/j.compbiomed.2020.103975). (WGCNA, CEMiTool, and coseq)
4. Show why our pipeline outperforms these tools in analyzing time series single cell data.
Suggested Methods:
1. Seurat (https://satijalab.org/seurat/index.html) for data prepocessing and other related packages such scran or scater in R software
2. Differential gene expression analysis
3. Kl divergence (Brownlee, 2019)
4. Functional PCA (Wu et al., 2014)
5. Spline smoothing (Storey et al., 2005)
6. Differential coexpression (Tesson et al., 2010)
7. Mutual information (concepts of information theory).
8. Constructing a Gene Co-Expression Network and Detecting Modules
9. Co-Expression Network Analysis
10. Functional enrichment analysis
Suggested data
Please use these data:
Covid19 data source: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE166766
refer to: https://pubmed.ncbi.nlm.nih.gov/33730024/
or any disease time series single cell data (cancer or diabetes, etc)
Software:
R programming or Python as second option
Potential journals to be published in: please check their paper structure or guidelines
1. Computers in Biology and Medicine
2. Bioinformatics
Outcomes:
1. Please provide all of the images, table and results of the pipeline code.
2. The code and data outcomes will be publicly accessed after publication.
Developing Leadership Skills
Developing Leadership Skills
This activity is designed to bridge the gap between talking about leadership and taking action to improve leadership skills. This is your opportunity to build a personal leadership development plan.
Instructions
Think about the leadership skills below and select five (5) you would like to improve upon:
Build trust
Coach others
Manage change
Assess performance
Create effective teams
With your five chosen skills, complete the following chart: Building a Leadership Development Plan Click for more options
Compose an essay in 400-500 words, double-spaced, that presents your leadership development plan, including an introduction, summary, and appendix. Include your completed Building a Leadership Development Plan chart as Appendix A, at the end of your paper. The Appendix does not count as part of the 400-500 word requirement.