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Bioinformatics Biology Report

Bioinformatics Biology Report

Overview:
• This practical report based on the results obtained from the “Whole genome sequencing for
identification and gene function prediction of bacterial genomes” pracs.
Details:
• Total marks available are 25
• You can submit a single Word Document/PDF file.
• The report should contains around 1500 words (excluding references) and contains the
following sections:

o Introduction
Include the following: 1) Application of whole genome sequencing in epidemiology
studies 2) What is spotty liver disease (SLD) in chickens and what bacteria is
responsible for the cause of SLD? 3) The aim of the practicals.
Material and Methods
Briefly describe the material and methods used in the pracs (for making libraries and
Bioinformatics), appropriately cite the sources of the methods
Results
Results presentations includes 1) name of species; 2) ANI value; 3) Number of coding
sequences and RNAs of your isolate ; 4) virulence genes ( you need to write from the
data and research out about some virulence for example: motility, invasion, ,) 5)
antibiotic resistance genes 6) plasmids ; 7) Subsystem Feature Counts (SEED Viewer)
Discussions
Interpretation of your findings, compare them with the literature: Is it the same species as
the bacteria known to cause SLD in chickens? What are the genomics and proteomics
features of the isolate and compare them to those of other common Campylobacter
species. The risk of antibiotic resistant plasmids present in bacteria isolated from poultry
sources. Here you need to write mor to show your understanding.
Conclusion
Write a short paragraph on the overall findings
References
All references mentioned in the text are correctly cited with consistent reference style for
every reference

Capital Budgeting and Cost of Capital Assignment

Capital Budgeting and Cost of Capital Assignment

For your Module 3 SLP assignment, continue to do research on the company that you wrote about for Modules 1 and 2. For this assignment, you will be estimating the weighted average cost of capital (WACC) for your chosen company. The final calculation will be fairly straightforward, as it involves just plugging in some numbers into an equation. However, the more challenging task will be finding the necessary numbers to plug into the formulas. You will need information such as the beta for your company, the bond-rating, and various information from its balance sheet. Links to some suggested Web pages for finding this kind of information is included in the instructions, but you might be able to find other sources of information. Go step by step and present your information for Steps 1-4 below in a Word document. Make sure to show all of your steps one by one and include the sources of your information:
Find out your chosen company’s credit rating. Rating agencies such as Moody’s and Standard and Poor’s assign ratings to companies. AAA is high, AA is lower, BBB is even lower, etc. The higher the rating, the lower the cost of debt capital. Explain what your company’s credit rating is and the reasons for the high or low rating based on your research. Also, use the Fidelity Fixed Income Web page to find out what the current return is for a 30-year bond for a corporation with the rating that your company has. This yield will be the approximate cost of debt capital for
your company. We will call the cost of debt RD.
Now estimate the cost of equity for your company. First you will need the beta; you already found this for your Module 1 SLP. You will also need the three-month treasury bill yield, which we will use as our measure of the risk-free rate. This rate should be listed on the Fidelity Fixed Income Web page linked above. Finally, you will need the equity risk premium. You can find estimates of this on many Web pages including Fidelity Fixed Income or Gutenberg Research. It is usually around 5%. Once you have this information, you can estimate the cost of equity as the 30-year treasury bill yield rate plus beta multiplied by the equity premium:
Cost of Equity = risk-free rate + Beta * (Equity Premium).
Show your calculations. We will call the cost of equity RE.
Now find out how much of the firm’s capital is equity and how much is debt. For the total value, look at the balance sheet for your company as found on Google Finance or a similar Web page. The total value of your company will be “total liabilities and shareholder’s equity.” The proportion of debt will be total liabilities divided by total value, which we will call D/V. The proportion of equity will be shareholder’s equity divided by total value, or E/V. If you calculate them correctly, the proportions will add up to one.
Now we have all the information we need to get at least a rough ballpark estimate of WACC. Let’s assume a corporate tax rate of 35%. So the formula we will use is WACC = (E/V)* RE +(D/V)* RD *(1-.35)
Calculate WACC and show your computations. As a “reality check” on your calculations, the WACC should likely be in the single digits and positive. Compare what you found to the average W  ACC in your company’s industry, which should be available on Web pages such as Cost of  Capital by Sector (US). Note that 35% is the official corporate tax rate, but many corporations find tax breaks. If your WACC is too low, try
computing it with a lower tax rate such as 25% or 10%.

SLP Assignment Expectations
Answer the assignment questions directly.
Stay focused on the precise assignment questions. Do not go off on tangents or devote a lot of space to summarizing general background materials.
For computational problems, make sure to show your work and explain your steps.
For short answer/short essay questions, make sure to reference your sources of information with both a bibliography and in-text citations.

Caterpillar Inc Case Study

Caterpillar Inc Case Study

Strategic Management Project Background document and Strategic Management Research Journal Entries

Review the Strategic Management Project Background document and your Strategic Management Research Journal entries from Weeks 1‑4.
Create a 12- to 14-slide presentation, complete with speaker notes for Caterpillar Inc.’s leadership team, in which you summarize your key findings, propose recommendations, and provide rationale with references for your recommendations.
Address the following topics and prompts in your presentation:
Topic: Caterpillar Inc.’s Vision
Summarize your evaluation of the alignment between what Caterpillar Inc. is currently doing and their mission, vision, or values statement.
Recommend any changes you would make to Caterpillar Inc.’s mission, vision, or values statements to improve organizational goals.
Topic: Caterpillar Inc.’s Competitive Advantages and Disadvantages
Summarize your analysis of the strengths and weaknesses of Caterpillar Inc.’s competitive advantages and disadvantages.
Recommend operational changes to improve Caterpillar Inc.’s competitive advantages and business performance.
Propose a plan to measure and monitor the effectiveness of your recommended operational changes in Caterpillar Inc.’s competitive advantages to achieve organizational goals.
Topic: Caterpillar’s Global Strategy
Summarize your assessment of Caterpillar Inc.’s global strategy.
Recommend operational changes to improve Caterpillar Inc.’s global strategy and business performance.
Propose a plan to measure and monitor the ef  fectiveness of your recommended operational changes to Caterpillar Inc.’s global strategy to achieve organizational goals.
References: List a minimum of 2 references researched for this Journal assignment.