Instructions

Writing introduction for the article of medicinal chemistry that title ” Design, synthesise and
antibuerlousis acrivity of novel compounds
writing introduction for the article of medicinal chemistry that title ” Design, synthesis and
antibuerlousis activity of novel compounds:
Should include the background and the significance of finding new treatment of tuberculosis
Below is the example:
Tuberculosis (TB) is one of the most common infectious diseases and continues to be a major
cause of morbidity and mortality worldwide (1). The emergence of HIV infection, decline of
socioeconomic standards, and a reduced emphasis on tuberculosis control programs have
contributed to the disease’s resurgence in industrialized countries (2,3). The lethal synergy of the
tuberculosis and human immunodeficiency virus (HIV) epidemics have complicated the global
fight against TB (4,5). Resistance of Mycobacterium tuberculosis strains to current antitubercular
agents, leading to the emergence of multidrug-resistant (MDR) M. tuberculosis strains, is an
increasing problem worldwide (5,6). These trends are predicted to continue for decades and
warrant the urgent need for new TB therapies (7)