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Herpes Zoster

Herpes Zoster

Herpes is a viral caused infection known as Herpes Zoster scientifically. Herpesviridae family of viruses is the main agents that cause the infection and consequently the infection surfaces itself differently (Gross 44). The two main viruses are herpes simplex virus1 and herpes simplex virus 2. Ramsay Hunt first identified herpes infection in late 1907 (Stanberry 31). He was the first scientist to document about the viral infection with the assistance of different scientists and no specific scientist is the chief discoverer. Symptoms of herpes zoster are very insignificant if present, may vary, and are dormant until during developed stages. Symptoms also vary regarding on which virus caused the infection. This research paper cites the various types of viruses, the type of herpes infection they cause, how persons contract and transmit the infections, ways to avoid infection and methods to control the infection once contracted.

The two main types of herpes zoster are oral herpes and genital herpes. Their symptoms are relatively different as they affect different parts of the body (Stanberry 71). Despite the fact that both viruses can cause either oral or genital herpes, herpes simplex virus 1 causes three quarters of lesions that occur in the case of oral herpes. Symptoms of these two types are also relatively different (Gross 56). In oral herpes zoster, cold sores round the mouth area are a dominant symptom of oral herpes. Infection causes painful sores on lips of the affected persons; this is especially common in infants aging from 9 months to 2 years. Gums develop small ulcers and it becomes painful to chew anything while the tongue becomes vulnerable to hot liquids and salty food due to open sores. In acute stages of oral herpes, blisters occur around the neck area and on the inner and outer areas of the cheeks (Gross 41). Small ulcers also occur on the upper areas of the mouth, which especially are sensitive to cold and heat. In addition, active muscles in the body become easily fatigued and ache most of times. Therefore, one becomes easily fatigued even while performing tasks requiring minimal effort (Stanberry 99).

Genital herpes mainly affects the anal areas of the affected individuals. Symptoms of this particular infection are diverse since they float up differently in different people. Mostly, some will have no significant signs while others build up stern symptoms. Gashes around anal and genital areas are a common feature in affected persons (Stanberry 105). The ulcers are usually several or can be one, but extended and painful especially when passing urine in women. This is so because the symptoms are not similar in both men and women. The ulcers dry up in several weeks, but not a sign of complete healing since the viruses are still present in the blood stream (Gross 60). Wounds are a symptom in acute stages of the infection and other mild and almost insignificant signs arise during early stages of the infection. Per se, the nodes of the victim may swell.

It is evident that the two viruses are different in many aspects such as the type of infection they cause. Ways in which a person can contract and transmit each type of virus are as well comparatively different. The herpes virus does not travel in air thus; one cannot contract the infection by breathing the same air as an infected person (Stanberry 17). Any type of herpes virus only spreads through direct contact with the infected part; this is with the case of herpes simplex virus 2. Exchange of body fluids from an infected body to unaffected body also is a way of transmission of herpes simplex virus 1 and herpes simplex 2 (Gross 80).

Saliva carries both types of the viruses but herpes simplex virus 1 is mainly in higher concentration than herpes simplex virus 2. Therefore, a direct deep kiss with a person having herpes ulcer(s) is a direct way to transmit virus to the unaffected person. If a person infected with oral herpes and has open herpes blisters haves oral sex, he, or she transmits the virus to his or her partner (Gross 89). A simple act of sharing the same cup or drinking soda from the same can with a person having herpes sores in the mouth can also spread virus to the unaffected person, but if the fluid dries before the virus is transmitted to another host, it is rendered quiescent (Stanberry 43)

Herpes simplex virus 2 mostly spreads from one host to another through sexual intercourse. If a person, having full of zip genital herpes and has developed lesions around the genitals or anal areas happens to have unprotected vaginal intercourse, he or she passes virus to his or her partner, which is also true in case of anal intercourse (Gross 100). It is important to note that, if one had suffered from oral herpes earlier he or she may be free from genital herpes even on having intercourse with an infected person. This is due to the immune developed in the body against herpes viruses after the first herpes simplex virus 1 attack (Stanberry 75). Herpes simplex virus 2 also transmits through direct skin contact with a person bearing the virus even if the person has no sores on the skin. This is because the virus can also dwell on the skin.

Herpes zoster can fall under the category of sexually transmitted infection and general measures taken to prevent contraction or transmission of sexually transmitted infections require practicing to control herpes zoster (Gross 76). Refraining from sex completely for single persons is an effective way to prevent contraction of the infection. For persons already having sexual partners, faithfulness to their partners is the only way to avoid contracting and transmitting the virus to their partners (Stanberry 90). People who have multiple sexual partners should use protection while indulging in intercourse with their partners to avoid multiple viral transfers.

Use of protection during intercourse however, does not guarantee full protection from contracting genital herpes. A condom may not envelop all the parts with herpes gashes and viral transfer is still possible (Gross 90) even when condoms are used. Thus, victims suffering from herpes zoster especially genital herpes should avoid indulging in sex completely during viral outbreaks. However, in between outbreaks, the virus is dormant, inactive, and it is relatively safe to have intercourse. There are different factors that render the virus active, exposure to subsequent infections being the common one and strong feelings such as trauma and pressure from stress. Thus, recurrent infections are common in many victims when under the mentioned factors (Stanberry 89).

As stated earlier herpes zoster is a viral disease and therefore have no cure and can only be suppressed or rendered dormant in the body (Stanberry 54). Attempts by renowned scientists and medical experts to make a cure are many but none has come up with one. Only methods to prevent reactivation of the viruses in the body keep increasing. The structure of the virus is what makes it difficult for experts to provide a cure (Gross50). A herpes simplex virus is able to penetrate in the thin membranes of body cells where the effect of drugs is almost zero. Since no vaccines against the infection are present yet, experts recommend consumption of unsullied fruits and green vegetables. They contain vital vitamins that are able to improve the body’s potential to fight against viruses.

In conclusion, herpes zoster is a viral infection and two main viruses causing it are the herpes simplex virus 1 and herpes simplex virus 2. Though the two viruses are of the same class, they cause two different types of herpes. Oral herpes, caused by herpes simplex virus1 and genital herpes caused by herpes simplex 2. The contraction and transmission of the two viruses from one host to another is as well different. Common methods of contraction are exchange of body fluids such as saliva, sexual intercourse either oral sex or vaginal sex with an infected person, or coming into direct contact with ulcers of a herpes victim (Gross 65). Sores around the mouth area are the dominant symptom of oral herpes and sores around the genitals and anal areas in case of genital herpes.

It is also evident that these sores occur in acute stages of the infection and there are other symptoms such as fever-like symptoms and flu especially in children. Herpes viruses do not pass through air but mainly through fluids. It is also in order to conclude that herpes infections have no cure and once the virus is in the body, suppressing it is the only available option. The viruses can remain dormant for a while but factors such as, pressure from stress and extreme shock can reactivate them (Stanberry 78).

Work cited

Stanberry, Lawrence. Understanding Herpes. Jackson: university press of Mississippi, 2006.

Gross, Gerd. Herpes Zoster. Amazon: Karger publishers, 2006.

Analysis-of-Variance

Statistical variances

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Analysis of Variance (ANOVA) is a collection of statistical method used to analyse and test the differences between group means and their connected procedures. In the ANOVA scenery the practical variance in a certain variable is subdivided into components attributable to diverse foundations of variation. The ANOVAS are vital for comparing three or more means. They provide statistical test of several groups and simplifies the t-test to more than two groups (Kanji, 2006).

When one needs to know if one measurement variable is connected with another one, then linear regression and correlation is essential. R It measures the strength of the association and makes an equation that is necessary to describe the relationship and predict indefinite values. linear regression and correlation are used when one has measuring variables. Correlation refers to the extent at which two variables are having a linear relationship with each other. It associates the relative position of cases along two variables. A relationship is said to be positive When there is an increase in the level of one variable and associated with the increase another. While a negative relationship occurs when there is an increase in one level and is associated with a decrease in the other. Correlation is used to represent association between two quantitative variables. the association is considered linear when one variable increases or decreases a stable amount for a module with an increase or decrease in the other. While regression involves approximating the best straight line to summarise the association (Bobko, 2001).

In this journal humprey claims that the method adopted shows neural nets are mathematical techniques rather than models of cognitive processing. applied mathematics is more than simply applying results from pure mathematics. models of meural nets are at times intimately associated with a learning algorithm (Humphreys, 2004).

The cross classified type of data examination is shared in research and evaluation, karl pearson’s chi square tests family represents the most utilized statistical analysis that answers questions about association among category variables. However, the results are commonly misinterpreted leading to statements that have limited statistical support from the analysis performed. This study focuses mainly on the chi-square tests of independence and homogeneity of variance. The reason for misinterpretation of tests in the Karl Pearson family of chi-square tests (independence, homogeneity, and goodness-of-fit) basically using the same formula. These three tests are different with particular hypotheses, sampling methodologies, interpretations, and options following refusal of the null hypothesis (Franke & et.al, 2011).

The Chi-square statistic is a distribution free test/ non-parametric tool that is designed to analyse group variances when the dependent variable is measured at a nominal level. It is used for testing hypothesis and when all variables measurement level is nominal or ordinary: the sample sizes of learning groups are unequal: The original is measured at an interval ratio but it violates the assumptions of homoscedasticity or equal variance. It allows evaluation of both multiple group studies and dichotomous independent variables, the calculations required for computing Chi-square provides considerable information of how each of the groups performed in the study. The advantages of the Chi-square are its robustness with respect to distribution of the data; its simplicity in computing; its use where parametric assumptions are not achieved and its elasticity in managing data from both two group and multiple group studies. The Limitations are; its sample size requirements (Mchugh, 2013).

Z-test is a statistical test with normal distribution that is applied and used for dealing with problems relating to large samples using population samples the study further explains classifications of z tests. Such as:

z test for single proportion tests a hypothesis on a particular value of the population proportion.

z test for difference of proportions tests the hypothesis that two populations have the same proportion.

z -test for single mean tests a hypothesis on a specific value of the population mean.

z test for single variance is used to test a hypothesis on a specific value of the population variance.

Z-test tests equality of variance as well as tests the hypothesis of equality of two population variances when the sample size of each sample is 30 or larger (Shasha, 2011).

REFERENCES

Bobko, P. (2001) Correlation and Regression: Application for industrial organizational

psychology and management. Thousand Oaks: Sage Publications

Franke, T.M, Ho, T., & Christie, C.A(2011). The Chi-square Test: Often Used and More

Often Misinterpreted. American Journal of Evaluation, 33(3). 448-458.

Doi:10.1177/1098214011426584

Humphreys P. (2004) Extending ourselves: Computational science, empiricism, and

scientific method. Oxford University Press, New York

Kanji, G.K. (2006). 100statistical tests. London: Sage Publications

Mchugh, M.L. (2013). The Chi-square test of independence. Biochemia Medica Biochem

Med, 143-149.doi 10.11613/bm.2013.018

Shasha, D.E., & Wilson, M. (2011). Statistics is easy! San Rafael, CA: Morgan & Claypool

Analysis-of-the-Impact-of-the-LGBTI-Community-on-Business

Analysis of the Impact of the LGBTI Community on Business

Violations to the rights of Lesbians Gays Bisexual and Transsexual community has been witnessed all over the state. The majority of the LGBT community have not had the pleasure of living their lives free from oppression. There fundamental rights have been disregarded and affected many individuals .In our case study we observed the true nature of how society has gained from the LGBTI community. Showing how the margin of business profits can be obtained if we embrace the community. There is a norm that LGBT community are spenders and will do anything to live a good life. The annual estimate shows that the buying power of the community is significantly high. In terms of figures the community spends roughly $800 billion in spending.

Companies have realized the benefit of the minority community. Changing market trends to get share of the enormous market. The impact of gay and lesbian consumers has been significant is Multinational Corporations such as apple, google Microsoft who have embraced the community (Howell, 2003). This has increased profit margins because no one would like to be associated with an unruly company. Sales are better and without the community they have survived. This might be true but going against the rights of LGBT some communities have suffered such as ExxonMobil.

Microsoft is an example of an MNC that has taken liberty to gain on the market. In the past Microsoft was under pressure from anti LGBT activities pertaining to a bill. The bill was to outlaw discrimination against homosexuals in work places in state of Washington. Due to pressure they withdrew from supporting it but later rejoined the quest to achieve it. The 2005 bill was rejected by a single vote in which Microsoft gave a press release on the Issue. It made significant claim that promoting diversity was a significant test to reduce administrative burdens and costs. Microsoft became the first company to expand its nondiscrimination policy to include sexual orientation, insurance and benefits to same sex domestic partners and health coverage to partially cover for transgender surgery. Due to their support there was a positive impact on employee satisfaction and in turn increased productivity and creativity.

The equality in workplace equality rights made employees comfortable and it generated enough talent from the most diverse pool of candidates. Microsoft ultimately influenced corporate behavior and this increased their stock performance because of the companies pro LGBT policies. It was observed that about 40% of gay shopping habits payoff for brands. Microsoft acknowledged that same sex households make more shopping trips than average U.S households. Gays and lesbians spend more frequently shopping on packaged goods and this was beneficially to Microsoft needs. Meaning that Microsoft had an upper hand to reach LGBT consumers and this influenced purchase behaviors and brand preference (David, 2006).

Profit soared to a higher level when the company initiated a group for gays and lesbians at Microsoft. It was noted that more consumers were Pro LGBT and this increased the market audience. LGBT consumers have less debt, and have more equity in their homes which means they are better financially set for retirement. The community has a higher national median according to an annually survey that was conducted (David, 2006).

Anti LGBT companies such as Exxon have a history for fighting against LGBT rights. Exxon a big oil company is known for their discrimination amongst the community. They had a big scandal about their employee selection when a capable individual who was gay was rejected because of his belief. The market was flooded with the story and this reduced their stock price and profits. Their fight against nondiscrimination protection and equal benefit coverage for employees impacted negatively on them. Mobil was acquired by ExxonMobil although it protected gay rights but eventually all rights were scrapped off. Upon acquiring Mobil a law suit was handed to them for discriminating LGBT employees as part of its hiring process. They were given a below zero score on its corporate equality index.

During a past decree by the president who signed an executive order barring federal contractors from transacting with anti LGBT discrimination. This dealt a significant blow to Exon-Mobil because it relied on contracts from the federal government. The US government declared that it would not do business with anti LGBT corporates and ExxonMobil was one of the companies that would be affected. The Oil Company had to redefine their policy In order to do business with the government. ExxonMobil witnessed its drop in profit margin due to reduced tender allocations. Annually they received an approximate of $1 billion in federal contracts and now they are losing the contracts. In simple terms Exxon would lose out on business which would lead to declining profits. NC corporate such as ExxonMobil would have a limited market to work with, they would be subjected to a lot of criticism from nations worldwide. Although in some nations the norm for same sex is never recognized it would seem they had a limited supply in regards to the big eight nations.

Pro LGBT policies are essential in growing a company’s productivity .They are better in creating a diverse environment to assist workers in nurturing the best talent. Target market is essential in increasing sales and being diverse is the best way forward.Anti LGBT policies are subject to discrimination reducing productivity in a company (Howell, 2003). To achieve growth one has to get the best employees to facilitate the increase in profits.In some countries such as Poland Singapore and others antigay laws are put in place to promote culture (David, 2006). In the USA the homophobic culture should be eliminated for the benefit of the whole nation. Taxes should be paid and benefits should be received to foster productivity. It is not true that pro LGBT will certainly give profits but it’s the sense of satisfaction that builds the growth. Employees should coexist to create a better future for the company as well as the nation.

Reference

Howell, M. (2003). Predators and Profits: 100 Ways for Investors to Protect Their Nest Eggs (pp. 127-156). Prentice Hall Professional.

David, J. (2006, January 26). Friends or foes. Advocate, 35-40.